BCHM310 Proteins - The Machines of Life

Updated: 25 October 2018
Credit Points 6
Offering
Responsible Campus Teaching Period Mode of Study
Armidale Trimester 1 Online
Armidale Trimester 1 On Campus
Intensive School(s)

Intensive schools are for students enrolled in Online Mode only, unless specified in the notes.

Start Finish Attendance Notes
02 May 2019 05 May 2019 Mandatory The intensive school is mandatory for both online and on-campus students. Students must attend the mandatory intensive school which is held in Armidale.
Supervised Exam There is a supervised exam at the end of the teaching period in which you are enrolled. The paper-based exam will be held at an established exam venue, and coordinated by UNE Exams Unit.
Pre-requisites BCHM210 or candidature in a postgraduate award
Co-requisites None
Restrictions BCHM510
Notes None
Combined Units BCHM510 - Proteins - The Machines of Life
Coordinator(s) Heather Nonhebel (hnonheb2@une.edu.au)
Unit Description

This unit focuses on protein structure and function, and analysis of proteins in the laboratory and by computer. Topics studied will include: an examination of protein structure and structural analysis; the relationship between protein structure and function in living organisms, studied using current examples; an introduction to protein evolution; the formation and degradation of native proteins in the cell including the targeting and post-translational processing of proteins; an introduction to protein engineering. Practical work will include protein isolation and assay; and introduction to protein databases. BCHM510 will cover material in greater depth than BCHM310, with separate assessments being completed.

Important Information

Where calculators are permitted in examinations, it must be selected from an approved list, which can be accessed from the Further Information link below.

Further information

Prescribed Material
Mandatory

Text(s):

Note: Students are expected to purchase prescribed material. Please note that textbook requirements may vary from one teaching period to the next.

Lehninger: Principles of Biochemistry

ISBN: 9781319108243
Nelson, D.L. and Cox, M.M., Worth 7th ed. 2017

Note: The 6th edition (ISBN: 9781429234146) can also be used.

Text refers to: Trimester 1, On Campus and Online

Referenced Material
Optional

Text(s):

Note: Reference material is held in the University Library - purchase is optional

Biochemistry

ISBN: 9780470570951
Voet, D. and Voet, J.G., Wiley 4th ed. 2010

Note: Available from the Dixson Library, UNE.

Text refers to: Trimester 1, On Campus and Online

How Proteins Work

ISBN: 9780815344469
Williamson, M., Garland Science 2011

Note: Available from the Dixson Library, UNE.

Text refers to: Trimester 1, On Campus and Online

Disclaimer Unit information may be subject to change prior to commencement of the teaching period.
Assessment
Must
Complete
Title Exam Length Weight Mode No. Words
Compulsory Assessment 1 5% 500
Assessment Notes

Online quiz on properties of amino acids. This quiz will count towards the final assessment of this unit.

Relates to Learning Outcomes (LO)

LO: 1

Compulsory Assessment 2 10% 500
Assessment Notes

Bioinformatics: Bioinformatic analysis of protein sequences. There is no word length stipulated (output = computer files + short answer questions). This assignment is mandatory and will count towards the final assessment of this unit.

Relates to Learning Outcomes (LO)

LO: 3

Compulsory Assessment 3 15% 1500
Assessment Notes

Essay. This essay is mandatory and will count towards the final assessment of this unit.

Relates to Learning Outcomes (LO)

LO: 1, 2

Compulsory Assessment 4 20% 1500
Assessment Notes

Practical Work and Presentation of Results. Students will be required to satisfactorily complete the practical work as well as the presentation of results as a spreadsheet, laboratory notebook and practical report. It is mandatory that students attend and pass this component in order to pass this unit.

Relates to Learning Outcomes (LO)

LO: 5, 6

Compulsory Final Examination 2 hrs 15 mins 50%
Assessment Notes

It is mandatory to pass this component in order to pass the unit.

Relates to Learning Outcomes (LO)

LO: 1, 2, 3, 4, 5, 6


Learning Outcomes (LO) Upon completion of this unit, students will be able to:
  1. understand basic principles of protein structure;
  2. use current examples to illustrate in detail the relationship between protein structure and function in a living organism;
  3. appreciate evolutionary relationships between proteins; be able to construct and interpret phylogenetic trees using protein sequences; and use a range of bioinformatic tools relating to proteins;
  4. describe how proteins are directed to cellular compartments, modified following translation, assisted to fold into their native state and specifically degraded;
  5. handle and assay proteins in the laboratory and be able to design a protocol for protein isolation and assay, showing how this relates to protein properties; and
  6. display skills in experimental design, execution, result interpretation and reporting.